Simple installation, use and programming as well as flexibility and efficiency are the factors that are increasingly driving the use of robots in the engineering sector. A growing trend, in Italy and abroad, that not only considerably simplifies the factory and increases its productivity, but also entails a considerable progress on the work front by delegating risky and repetitive tasks, with low added value, to industrial and collaborative robots. But not all robots are the same or capable of the same ‘miracles’. This is evident when analysing the collaboration that has grown between a leading multinational company in automation and industrial robotics and a globally-recognised excellence in the development, production and sale of highly technological components for machine tools. A collaboration that has made a difference, because it has led to the development of a state of the art robot-spindle application.